EphrinB2 and -B3 are coexpressed in the cerebral cortex, but ephrinB3 is distinctly expressed in the brain stem. (A and B) A three-dimensional model of the adult mouse brain was colored differently to represent the three major brain regions, i.e., the cerebral cortex (light blue), the cerebellum (green), and the brain stem (purple). The left hemisphere of the mouse brain was viewed from either a dorsal plane (A, C, and E) or a sagittal plane (B, D, and F). EphrinB2 expression in the cerebral cortex (C) or the brain stem (D) is indicated by orange and yellow dots. EphrinB3 expression in the cerebral cortex (E) or the brain stem (F) is displayed as red dots. All images were created using Brain Explorer v1.3, the Allen Brain Atlas (28) gene expression viewer program.