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Profiles of plasma viral RNA loads (A) and circulating CD4+ T lymphocytes (B) in two macaques infected with M-tropic SHIV891631 (5,000 TCID50). One rhesus monkey (R447) was infected with the highly pathogenic T-cell-tropic SHIVDH12R (5,000 TCID50). The insets show measurements made during the first 25 weeks of the infections. The detection limit of our RT-PCR assay is 200 RNA copies/ml, and undetectable values are plotted as 100 RNA copies/ml of plasma. †, time of euthanasia.
