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. 2007 Aug 8;81(20):11341–11351. doi: 10.1128/JVI.00930-07

TABLE 2.

Progressive substitutions of dominant nucleotides in the consensus O Tw97 genome sequence during pig passage

Pig designationc Infectious roundd Nucleotide in indicated position and region
Nucleotide in indicated position and region
5′ UTRa
3′ UTR
Lpro
P1
P2
P3
82b 155 403 474 480 524 541 818 844 955 8096 1087 1411 1444 1522 1573 1611 2290 2793 2860 2881 2890 3040 3724 3763 4015 4252 4426 4438 4469 4779 5002 2032 5107 5257 5276 5291 5656 5986 6283 6311 6364 6641 7076 7183 7375 7561 7792
Parental O Tw97e T T G A G A C T A A T A G A T T A A A C T C A T A C T G A G C C C A C A C T G T C T G A C C C C
48 T00v1
48 T00v2
48 T00v3
50 T00v1
50 T00v2
50 T00v3
483 T0
484 T1 T
485 T1 C G T
486 T2 G T
487 T2 G A C C
488 T3 G A C T
489 T3 A A C
490 T4 G A A C C T
491 T4 G A A C T
492 T5 G A A C C C T
493 T5 G A A C C T
494 T6 G A A C C T
495 T6 G G A C C T
496 T7 A C C T
497 T7 C T G A C T A T
498 T8 C G G A C A T
499 T8 C G A C T A T
725 T9 C G G G A C A T
726 T9 C T G A C T A T
4500 T10 C G A C A T
5008 T10 C A C T G A T
5009 T11 C A C T G A T
5010 T11 C G A T C T G A G T
5011 T12 C G A T C T G A G T
5012 T12 C G G A T C T G A G T
5013 T13 C G G A T C C A T T G A G T
5014 T13 C G G A T C T G A G T
5015 T14 C A G G A G G T C T G A T G T
5016 T14
4823 T15 (14-I) C A T G T
4824 T16 C G A G G A C T C G T
4825 T17 C G G A G C G T C A G T G A T C G T T T
4826 T17 C G A G G A G C C T G A G T T
5184 T18 C G A C G T G A T C G T T
5185 T18 C A G G A C G T G A T C G T T
5005 T19 (18-I) C C G G G A G G T T T G T A T C G T T T
5006 T20 C C G G G G A G C C G G T C G T G A T C G T T
5007 T20 C G G A G T C T G A T C G T T
a

Genomic regions include UTRs and precursor protein-coding regions.

b

Specific position number in the full-length O Tw97 genome (GenBank accession no. AY593835).

c

Pig identification number.

d

The infectious round represented by each pig number is shown, followed by the nucleotide substitutions detected in the corresponding consensus sequence. Empty spaces indicate no change of nucleotides with respect to the parental O Tw97 sequence.

e

The O Tw97 row indicates the nucleotides assigned for the parental consensus O Tw97 sequence.