. 2007 Aug 8;81(20):11139–11147. doi: 10.1128/JVI.01235-07

TABLE 1.

Mouse infectivity titers of H7 viruses

Virus	Name in this study	Subtype	Intravenous pathogenicity index	Patient symptoms^a	MID₅₀^b	LD₅₀^b	% Maximum wt loss^c	HA cleavage site sequence^a
A/Netherlands/219/03	NL/219	H7N7	HPAI	Fatal ARDS	0.76	2.5	23.7	PEIPKRRRR/G
A/Netherlands/230/03	NL/230	H7N7	HPAI	Conjunctivitis	2.5	>7	14.5	PEIPKRRRR/G
A/Ck/Netherlands/1/03	Ck/NL/1	H7N7	HPAI	NA	3.25	>7	12.5	PEIPKRRRR/G
A/Canada/504/04	Can/504	H7N3	HPAI	Conjunctivitis	2.25	>7	2.5	PENPKQAYQKRMTR/G
A/Canada/444/04	Can/444	H7N3	LPAI	Conjunctivitis	2.5	>7	2.5	PENPKQAYQKQMTR/G
A/NY/107/03	NY/107	H7N2	LPAI	Respiratory symptoms	2.25	>7	12.2	PEKPKPR/G
A/Tky/VA/4529/02	Tky/VA	H7N2	LPAI	NA	1.76	>7	3.5	PEKPKPR/G
A/Ck/CT/260413-2/03	Ck/CT	H7N2	LPAI	NA	2.25	>7	10.1	PEKPKPR/G
A/GH/Mass/148081-11/02	GH/Mass	H7N2	LPAI	NA	1.5	>7	16.1	PEKPKKR/G

As described previously (6, 12, 16, 41). NA, not applicable.

MID₅₀ and LD₅₀ values are expressed as the EID₅₀ required to give 1 MID₅₀ or 1 LD₅₀, respectively.

Average percent maximum weight loss at height of infection (five mice per group) following i.n. infection at 10⁶ EID₅₀/50 μl.