TABLE 3.
Virus titers in corneasa
| Mouse group | Virus titer (log10 PFU/ml) at day 3 p.i. |
|---|---|
| WT | 3.2 ± 0.18 |
| TLR4−/− | 3.7 ± 0.21 |
| TLR9−/− | 3.3 ± 0.17 |
| TLR2−/− | 3.1 ± 0.08 |
| MyD88−/− | 3.2 ± 0.10 |
Mice were infected with 3 × 105 PFU of HSV-1 RE. Virus titers were estimated by standard plaque assay from swabs taken from infected corneas of mice (n = 4) at different time points. Virus was not detected, i.e., was below the sensitivity of the assay (<10 PFU/ml), for all corneas taken at day 7 p.i.