TABLE 3.
Plasma half-lives of the three MAbsa
| Subject |
T1/2 α (days)
|
T1/2 β (days)
|
||||
|---|---|---|---|---|---|---|
| 2G12 | 4E10 | 2F5 | 2G12 | 4E10 | 2F5 | |
| 700 | 0.55 | 0.66 | 0.52 | 14.71 | 5.89 | 3.64 |
| 701 | 0.59 | 0.67 | 0.62 | 26.86 | 11.41 | 8.52 |
| 702 | 0.73 | 0.68 | 0.65 | 19.02 | 7.13 | 6.68 |
| 703 | 0.71 | 0.58 | 0.65 | 20.64 | 7.04 | 7.45 |
| 704 | 0.73 | 0.71 | 0.67 | 19.11 | 7.77 | 4.80 |
| 705 | 0.61 | 0.54 | 0.56 | 26.13 | 6.68 | 5.12 |
| 706 | 0.65 | 0.45 | 0.47 | 17.97 | 8.32 | 5.75 |
| 707 | 0.71 | 0.58 | 0.59 | 19.40 | 8.64 | 5.26 |
| 708 | 0.64 | 0.53 | 0.67 | 13.25 | 7.62 | 5.45 |
| 709 | 0.73 | 0.79 | 0.71 | 21.83 | 7.28 | 5.24 |
| Mean | 0.67 | 0.62 | 0.61 | 19.89 | 7.78 | 5.79 |
| SD | 0.07 | 0.10 | 0.08 | 4.32 | 1.50 | 1.40 |
T1/2 α, first-phase elimination half-life.