Table 4.
Genotype frequency of the i-T744C SNP of the P2RY12 gene according to smoking habit
| Smokers (n = 809) | Non-smokers (n = 503) | |||||
| CAD | CAD-free | OR (CI 95%) p-value * | CAD | CAD-free | OR (CI 95%) p-value * | |
| T/T | 490 (75.4%) | 121 (76.1%) | 221 (72.5%) | 164 (82.8%) | ||
| T/C | 150 (23%) | 35 (22%) | 1.04 (0.69–1.56) |
81 (26.5%) | 28 (14.2%) | 1.83 |
| C/C | 10 (1.6%) | 3 (1.9%) | p = 0.85 | 3 (1%) | 6 (3%) | (1.17–2.87) |
| TC+CC | 160 (24.6%) | 38 (23.9%) | 84 (27.5%) | 34 (17.2%) | p = 0.007 | |
*T/C and C/C genotypes (H1/H2 and H2/H2 haplotypes, respectively) are pooled in the CAD and in the CAD-free group for p-value and OR calculation.