Figure 4.

Subcellular localization of protein interactions. A, A network subset of medium confidence interacting proteins where proteins were assigned to a subcellular compartment in the SUBA database. B, Analysis of all interacting protein pairs in which both partners were assigned to a subcellular compartment. The numbers of individual protein numbers is in italics beside compartment names. Compartment pairs that showed enriched or depleted numbers of interactions (compared to chance) are color coded. For example, there is a significant (P < 0.01) enrichment of interactions in which both partners are nuclear localized, while there is a significant depletion of interactions between nuclear and vacuolar localized proteins. Chloro, Chloroplast; Cyskel, cytoskeleton; Excell, extracellular; Mito, mitochondria; Perox, peroxisome.