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. 2007 Nov 14;2(11):e1167. doi: 10.1371/journal.pone.0001167

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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Two full-thickness dermal wounds were induced in NAS mice and nontransgenic mice, vehicle-treated control mice, g-secretase inhibitor (GSI)-treated (100 µM DAPT) mice and 15 µM mouse Jagged peptide-treated mice. a. Images of a representative mouse from each group taken on post-injury days 1, 3, 5, 8 and 13 are shown. b. Wound sizes at the indicated time points in NAS and wild-type control mice (WT). c. Wound sizes at the indicated time points in control, GSI-treated and Jagged peptide-treated mice. Values are the mean and SEM (n = 6 mice per group). *p<0.001, #p<0.01 compared to the control value. Scale bar = 4 mm.