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. 2007 Nov 14;2(11):e1167. doi: 10.1371/journal.pone.0001167

Figure 2. Histological features of wound healing in mice with decreased or increased Notch activity.

Figure 2

Images of skin tissue sections stained with hematoxylin and eosin showing histological changes during the wound healing process in non-transgenic control mice, NAS mice, GSI (100 µM DAPT) treated mice and 15 µM Jagged peptide-treated mice at post-injury days 1, 3, 5, 8 and 13. NAS and DAPT-treated mice exhibited delayed wound healing, and Jagged peptide-treated exhibited enhanced wound healing, compared to control mice. See Supplementary histological evaluation (Text S2) for a detailed description of histological changes in the different groups of mice. Scale bar = 0.5 mm