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. Author manuscript; available in PMC: 2007 Nov 1.
Published in final edited form as: Brain Res. 2007 Aug 10;1171:83–92. doi: 10.1016/j.brainres.2007.06.102

Table 1.

Coordinates of major activation clusters in the Talairach frame of reference and average t-scores in 0.73 cc isotropic ROI centered at these coordinates. Statistical significance (corrected for multiple comparisons): Pcorr < 0.001 (bold); Pcorr < 0.05 (†). (*): Pcorr < 0.05 with small volume correction (spherical; searching radius = 10mm). S: cocaine. C: Controls. The 0, 1, and 2 column labels indicate 0-, 1-, and 2-back tasks. WM-load: 2-back minus 1-back.

Coord [mm] Control (C; n=16) Cocaine (S; n=16) S > C WM-load
Brain Region  x   y   z   0   1   2    0     1     2     0     1     2     C     S   S > C
IFG47 L ‑33 18 ‑3 2.4 3.5 5.0 2.2 ‑2.2
R 33 18 ‑3 2.9† 3.2 6.0 3.3 4.7 4.6 2.2
MFG9 L ‑45 9 33 6.2 9.4 9.7 11.5 ‑2.1 2.6† 2.7
R 45 9 33 4.6 8.5 7.1 6.5 3.1† ‑2.5*
MFG9 L ‑45 27 21 4.8 9.0 3.6 8.5 3.4 3.4†
R 45 27 21 2.5 5.8 4.7 8.1 2.5† 2.5
MFG6 L ‑39 ‑6 51 3.1 6.3 4.1 2.6 5.2 3.2
L ‑24 0 51 3.2 4.5 10.2 3.3 4.7 2.4† 4.0
C ‑9 3 60 2.5 2.4 3.3 2.6 9.9 7.6 5.4 2.8
SFG8 C 3 27 51 3.7 6.3 3.2 4.4
medFG8 C ‑6 18 45 4.2 7.3 11 9.8 13.8 ‑2.3 3.0* 2.8†
ACG24 C ‑6 24 21 ‑2.1 ‑4.0 ‑5.8 ‑2.1 ‑3.1* ‑4.7
Putamen L ‑24 12 ‑3 ‑2.7 ‑4.7 ‑2.8† ‑3.8
R 24 6 15 ‑2.6 ‑5.4 ‑2.4* ‑4.4 ‑2.0
INS13 R 45 ‑6 6 ‑3.7 ‑6.6 ‑9.9 ‑3.7† ‑4.1 ‑2.4
Tha/Mes C ‑6 ‑15 ‑3 2.4 3.8 3.4 ‑2.1* ‑2.5*
PHG/Amy L ‑30 ‑3 ‑15 ‑3.2 ‑6.8 ‑3.3 ‑2.6*
R 30 ‑3 ‑15 ‑3.4 ‑5.8 ‑2.4† ‑3.4
PCG30 C ‑6 ‑51 18 ‑5.8 ‑8.5 ‑12 ‑2.0† ‑6.0 ‑8.4 2.2 3.0 ‑3.1
PostCG5 L ‑42 ‑24 54 ‑2.4 2.4 3.5 2.3 2.1 4.1 2.0
PostCG3 R 39 ‑30 51 3.0 2.0 5.7 6.7 3.4 2.4
IPC40 L ‑30 ‑42 54 3.8† 7.9 10.2 3.2 6.2 6.3
SPC7 L ‑33 ‑57 51 2.2 6.0 8.8 4.7 10.6 2.5† 4.2
R 33 ‑48 57 5.9 10 7.5 9.9 3.7
L ‑21 ‑54 54 3.8 7.4 11.6 4.8 5.1 2.3† 3.0
PreCUN7 R 18 ‑63 42 4.6 9.1 ‑3.0† ‑6.5 3.5 ‑2.7*
PreCUN39 L ‑36 ‑66 39 3.1 ‑4.0 ‑3.9 ‑2.5 ‑4.9† 2.6†
FusG19 L ‑33 ‑66 ‑15 4.2 5.1 8.8 10.6 3.3 3.5
R 36 ‑78 ‑6 2.8 3.5
LG17 L ‑24 ‑81 ‑9 4.9 4.9 3.1 3.2
CER L ‑12 ‑51 ‑18 2.7† 2.9 ‑2.6 ‑2.3 ‑3.9† 6.2 2.0*
C 0 ‑72 ‑15 3.2† 6.4 7.0 2.0 7.1 7.8