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. 2007 Sep 18;7:247. doi: 10.1186/1471-2458-7-247

Table 3.

SAFs*, hospital diagnoses and acute care hospital days attributable to smoking for major disease categories in Canada, 2002

Disease condition (for definition by ICD 10 see Table 1) Number of diagnoses Hospital days
SAF in % (all ages) mean age at diagnosis Smoking-attributable diagnoses SAF in % (all ages) Smoking-attributable hospital days

M F M F M F Overall M F M F Overall

ACTIVE SMOKERS
Malignant neoplasms
 Oropharyngeal cancer 58.7 51.3 59.6 60.1 2,128 1,116 3,244 34.8 30.2 13,302 6,125 19,427
 Oesophageal cancer 48.8 40.0 66.4 68.8 1,338 387 1,725 29.4 23.6 9,453 3,140 12,593
 Stomach Cancer 16.4 12.5 67.0 66.1 546 233 780 9.8 7.4 4,308 2,068 6,376
 Pancreatic cancer 17.7 13.4 65.6 67.5 623 478 1,101 10.4 8.0 4,189 3,831 8,021
 Laryngeal cancer 67.7 60.8 65.8 64.2 950 236 1,187 40.4 35.6 7,637 1,815 9,452
 Lung cancer 88.6 63.8 68.6 66.2 18,488 10,441 28,929 53.4 37.9 124,082 75,280 199,362
 Cervical cancer -- 36.4 -- 48.5 -- 1,381 1,381 -- 21.4 -- 4,807 4,807
 Urinary tract 55.6 38.3 68.7 68.2 8,336 2,392 10,728 33.2 22.6 38,017 13,149 51,165
 Renal cell carcinoma 26.0 7.5 63.7 62.0 993 176 1,169 15.7 4.2 5,996 1,116 7,112
 Bladder cancer 67.7 52.4 72.5 72.6 7,336 1,832 9,169 40.9 31.3 29,288 8,604 37,892
 Acute myeloid leukemia 21.9 17.7 59.2 56.4 465 310 775 12.8 10.7 4,461 3,316 7,777
Total malignant neoplasms 32,875 16,974 49,849 205,449 113,530 318,979
Tobacco abuse
 Tobacco abuse 100.0 100.0 55.6 52.9 4,042 3,481 7,522 100.0 100.0 18,204 15,776 33,979
 Toxic effect of tobacco and nicotine 100.0 100.0 29.5 37.0 7 7 14 100.0 100.0 9 30 39
Total tobacco abuse 4,049 3,488 7,536 18,213 15,805 34,018
Cardiovascular diseases
 Ischaemic heart disease
 Age < 45 yrs 51.4 44.3 36.6 36.3 6,534 1,758 8,293 30.4 26.5 20,044 6,548 26,593
 45–59 yrs 42.2 37.3 52.0 52.0 32,360 8,979 41,339 25.2 22.3 119,120 36,466 155,586
 60–69 yrs 29.1 23.4 64.5 64.5 22,681 8,294 30,975 17.4 14.0 103,449 42,245 145,694
 70–79 yrs 10.0 7.3 74.5 74.5 9,346 4,518 13,865 6.0 4.3 52,164 26,986 79,150
 80+ yrs 8.9 5.1 87.0 87.0 4,891 3,340 8,232 5.3 3.1 32,243 24,358 56,601
 Pulmonary circulatory disease 81.0 76.4 65.2 65.8 9,251 10,601 19,852 47.9 44.9 81,952 90,735 172,687
 Cardiac arrythmias
 Age < 45 yrs 43.6 37.5 33.6 32.9 2,025 1,323 3,348 24.7 20.5 9,158 5,577 14,735
 45–59 yrs 42.2 37.3 52.0 52.0 5,483 2,348 7,832 25.2 22.2 29,911 12,656 42,568
 60–69 yrs 29.1 23.4 64.5 64.5 5,782 2,650 8,432 17.3 13.9 35,626 16,305 51,931
 70–79 yrs 10.0 7.3 74.5 74.5 3,493 2,069 5,562 6.0 4.3 24,437 14,648 39,084
 80+ yrs 8.9 5.1 87.0 87.0 2,439 2,011 4,450 5.3 3.1 19,254 16,975 36,228
 Heart failure
 Age < 45 yrs 41.0 31.7 34.1 34.2 1,005 631 1,635 23.5 18.0 6,764 4,771 11,535
 45–59 yrs 42.2 37.3 52.0 52.0 3,841 1,904 5,745 25.2 22.3 24,850 13,435 38,285
 60–69 yrs 29.1 23.4 64.5 64.5 4,553 2,517 7,070 17.4 14.0 31,466 18,134 49,600
 70–79 yrs 10.0 7.3 74.5 74.5 3,008 1,911 4,918 6.0 4.3 22,437 15,173 37,610
 80+ yrs 8.9 5.1 87.0 87.0 2,748 2,319 5,066 5.3 3.1 22,183 20,520 42,703
 Cerebrovascular diseases
 Age < 65 yrs 39.1 35.4 52.8 50.5 5,033 3,449 8,482 23.5 21.3 45,470 32,326 77,796
 > = 65 yrs 14.7 10.5 76.9 78.4 5,535 4,113 9,647 8.8 6.2 58,485 48,105 106,589
 Atherosclerosis 33.5 36.9 68.9 69.4 14,036 9,896 23,933 19.8 21.7 109,603 80,842 190,445
Total cardiovascular diseases 62.2 65.2 144,044 74,631 218,675 848,617 526,806 1,375,423
Respiratory diseases
 Pneumonia & Influenza 17.3 12.8 69.4 68.3 13,246 8,648 21,894 11.5 8.3 118,770 74,914 193,684
 Chronic obstructive pulmonary disease 82.6 76.9 67.0 66.8 5,268 4,463 9,731 49.3 45.5 32,022 27,608 59,630
Total respiratory diseases 68.7 67.8 18,514 13,111 31,625 150,793 102,522 253,315
Intestinal diseases
 Ulcer 47.7 38.4 65.4 68.3 6,237 4,026 10,263 28.8 22.6 45,416 31,551 76,967
Perinatal period
 Low birthweight and short gestation 24.7 20.6 0.0 0.0 6,770 5,057 11,827 14.8 12.3 59,906 42,580 102,485
 Sudden infant death syndrome 31.2 26.5 0.0 0.0 2 1 3 19.6 16.7 2 0 2
Total perinatal diseases 0.0 0.0 6,772 5,059 11,832 59,907 42,580 102,487
Injury
 Fire injury 24.6 23.4 44.9 53.9 244 101 346 24.6 24.6 1,529 737 2,266
Total active smokers 61.6 62.3 212,735 117,390 330,126 1,329,923 833,531 2,163,455
PASSIVE SMOKERS
 Lung cancer 1.6 1.4 66.5 65.2 330 231 561 0.9 0.8 2,163 1,643 3,806
 Ischaemic heart disease 1.8 1.5 64.7 70.5 5,725 2,768 8,493 1.0 0.8 27,073 15,821 42,894
Total passive smokers 64.8 70.1 6,056 2,999 9,054 29,235 17,465 46,700
TOTAL SMOKING-ATTRIBUTABLE 61.9 62.8 218,791 120,389 339,179 1,359,159 850,996 2,210,155

* The SAF (smoking attributable fraction) is the fraction of the disease in the population that would not have occurred if the effect associated with smoking was absent. It is calculated by means of a formula that combines prevalence of smoking and relative risk of a particular disease. The SAF is then applied to the total number of occurrences of disease to estimate the number of occurrences that are attributable to smoking.