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Intracellular concentrations of ciclesonide and fluticasone propionate in A549 cells during incubation with 2 × 10-8 M ciclesonide or fluticasone propionate. Concentrations of ciclesonide represent the sum of the intracellular concentrations of ciclesonide, des-CIC, and fatty acid esters of des-CIC. Results represent the mean ± standard deviation from 5 dishes per time point. *** p < 0.001 for ciclesonide versus fluticasone propionate (Aspin-Welch t-test).
