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. 2007 Sep 27;7:12. doi: 10.1186/1471-2210-7-12

Table 1.

Intracellular concentrations of ciclesonide, des-CIC, and des-CIC-oleate during incubation with 2 × 10-8 M ciclesonide

Incubation time (min) Mean concentration ± SD (pmol/dish)a)

Ciclesonide des-CIC des-CIC-oleateb)
3 15.04 ± 2.48 0.41 ± 0.05 0.00 ± 0.00
5 17.86 ± 2.30 0.33 ± 0.19 0.00 ± 0.00
10 36.63 ± 23.48 0.67 ± 0.13 0.02 ± 0.05
20 34.22 ± 9.15 0.97 ± 0.14 0.12 ± 0.07
30 48.21 ± 5.19 1.72 ± 0.14 0.40 ± 0.06

a) 5 dishes per time point

b) Conjugates of des-CIC with palmitic acid were almost undetectable.