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Rates of aminotransferase elevation and drug discontinuation for available statins
| Statin | Number of prescriptions written in 2004 (in millions) | Incidence of AST or ALT level > 3 times ULN | Rate of discontinuation |
|---|---|---|---|
| atorvastatin | 62.5 | 0-0.7% | n/a |
| fluvastatin | 1.9 | 1.2% | 0.6% |
| lovastatin | 7.4 | 0.6% | 0.2% |
| pravastatin | 12.0 | 1.3% | 0.1% |
| rosuvastatin | 6.3 | 0% | 0% |
| simvastatin | 23.8 | 1.8% | 0.5% |
