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. Author manuscript; available in PMC: 2008 Jul 15.
Published in final edited form as: Dev Biol. 2007 May 3;307(2):214–226. doi: 10.1016/j.ydbio.2007.04.039

Figure 3.

Figure 3

Somite segmentation and PSM maturation is disrupted in SBU2 mutants. Whole mount RNA in situ hybridization of genes involved in somite segmentation process in wild-type and SBU2 mutants. All views are dorsal; anterior to the top. In wild type embryos, periodic activation of notch signaling provides cycling gene expression of Notch pathway genes such as her1 and her7 (A-D and E-H). dld expression is weak and diffused in presomitic mesoderm as well as anteriormost somites (I-L). tbx24, normally expressed in intermediate and anterior PSM, is also reduced in SBU2 embryos (M-P). Arrows denote stripes of her1, her7 or dld expression.