Figure 4. Cardiac power is decreased with Western diet in the long term.

Cardiac power (A), MV˙O₂ (B), oleate oxidation (C) and glucose oxidation (D) at baseline (solid circles) and in response to an acute increase in work (open points) in the acute (AT), short (ST), intermediate (IT), and long term (LT) on low fat, Western or high fat diet. Values are means±S.E.M. for 12–18 independent experiments per group. Flux is represented per minute per gram dry weight (gdw). Closed squares (■) represent low fat diet-fed rats, closed circles (●) represent Western diet-fed rats and closed triangles (▲) represent high fat-fed rats at baseline. Open squares (□) represent low fat diet-fed rats, open circles (○) represent Western diet-fed rats and open triangles (△) represent high fat diet-fed rats after an acute increase in work. *, P<0.05, **, P<0.01 and ***, P<0.001 compared with low fat diet at the same age. $, P<0.05 compared with Western diet at the same age.