Table 3.

Odds Ratios and 95% Confidence Intervals of Developing a Worsening of Functional Difficulty (an Increase in 2 or More Points on the 0–12 Scale) at 6-Year Follow-Up

Model	No Impairment	mMMSE Only Impaired	Trails B Only Impaired	Both Impaired
ADL
Unadjusted	1.0	1.25 (0.92, 1.71)	2.37 (1.94, 2.89)	2.80 (1.95, 4.03)
Age adjusted	1.0	1.14 (0.83, 1.56)	1.82 (1.48, 2.24)	1.84 (1.26, 2.69)
Adjusted for age, education, comorbidities, GDS, baseline ADL	1.0	1.10 (0.77, 1.58)	1.48 (1.16, 1.89)	1.31 (0.84, 2.04)
IADL
Unadjusted	1.0	1.22 (0.93, 1.58)	1.80 (1.50, 2.16)	2.44 (1.74, 3.41)
Age adjusted	1.0	1.11 (0.85, 1.46)	1.39 (1.15, 1.68)	1.63 (1.15, 2.31)
Adjusted for age, education, comorbidities, GDS, baseline ADL	1.0	1.09 (0.80, 1.49)	1.23 (0.98, 1.54)	1.22 (0.81, 1.83)

Note: mMMSE = modified Mini-Mental State Examination; Trails B = Trail Making Test B; ADL = Activities of Daily Living; GDS = Geriatric Depression Scale; IADL = Instrumental Activities of Daily Living.