Table 1.
Treatment | Time Post Treatment | Shrunk/Total Neuronsa | TUNEL positiveb |
---|---|---|---|
Sham | 1 week | 0.022 ± 0.0015 | 2.0 ± 1.0 |
Smoke | 1 week | 0.019 ± 0.0004 | 2.3 ± 1.3 |
Sham | 8 weeks | 0.026 ± 0.0015 | 1.6 ± 1.3 |
Smoke | 8 weeks | 0.060 ± 0.0030* | 5.7 ± 1.6* |
Sham | 10 weeks | 0.025 ± 0.0015 | 2.3 ± 1.6 |
Smoke | 10 weeks | 0.071 ± 0.0012* | 6.2 ± 0.3* |
Values are means ± SD given as
ratios of shrunk to total neurons and
counts of TUNEL positive cells (n=3). Counting was done in a blinded fashion and each section was counted three times. Counts were analyzed by ANOVA for a two factorial experiment; the two factors were treatment (smoke inhalation or sham) and harvest time (1, 8, and 10 weeks).
P<0.05 vs. sham control