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Comparison of the structures of licofelone and MK-886. (a) Chemical structures of licofelone and MK-886. (b) Flexible alignment of licofelone and MK-886 showing mutual PPPs. Green shapes represent lipophilic features, red ones show potential hydrogen-bond acceptors, and the polar group (carboxy function) is displayed in magenta. PPP, potential pharmacophore point.
