Figure 1.

Fixation probability of a new mutation occurring in a self-fertilizing line plotted against its selection coefficient s. The fitnesses of the wild-type, heterozygote, and mutant genotypes were 1, 1 − hs, and 1 − s, respectively. For the case of selfing, it can be shown that the function relating fixation probability (u) and s is u = (1 − s)/(2 − s), and the mean time to fixation or loss is three generations. Fixation probability is independent of h, the degree of dominance of the mutation.