Relationship of GluR6 genotype to the amount of residual variation of the age of onset of HD, after the HD CAG repeats have been accounted for. Expected age of onset was determined by using the formula: log(age) = α + β(CAG repeat number), where α = 6.15 and β = −0.053. For each genotype, the median value is indicated as an open bar, the 95% confidence interval is indicated as the solid box, the range is indicated by brackets, and outlying points by solid lines. Genotypes are indicated by allele sizes in base pairs. Genotypes and the corresponding number of cases are as follows: 143,143, 1 case; 146,134, 1 case; 146,143, 2 cases; 146,146, 2 cases; 149,140, 2 cases; 149,143, 17 cases; 149,146, 30 cases; 149,149, 129 cases; 152,143, 7 cases; 152,146, 9 cases; 152,149, 56 cases; 152,152, 10 cases; 155,143, 1 case; 155,149, 4 cases; 155,152, 1 case; 155,155, 4 cases; 158,146, 1 case; 158,149, 1 case.