Figure 3.

Effects of decorin and LAP on mycobacterial replication in MN in vitro. MN were infected with MTB (H37Ra) and cultured for up to 7 days in medium alone or medium containing optimal concentrations of antibody to TGF-β (anti-TGF-β) (10 μg/ml), decorin (DEC) (50 μg/ml), LAP (100 ng/ml), BSA (50 mg/ml), or recombinant TGF-β (10 ng/ml). Mycobacterial replication was assessed in the cfu assay. Results represent mean ± SE cfu/ml, n = 4. *, P ≤ 0.0001; **, P ≤ 0.006; ***, P ≤ 0.01 as compared with mycobacterium-infected MN cultured in medium alone (MN).