Table 2.

Relative resistance to U-90152 conferred by different RT mutations

	L100I	K103N	V106A	V179A	Y181C	P236L
Dueweke et al. (24)*	—	30×	—	—	32×	—
Dueweke et al. (27)*	—	30×	—	—	32×	70×
Romero et al. (40)*	—	—	—	—	8×	>100×
Fan et al. (28)†	—	—	—	—	—	25×
Balzarini et al. (41)‡	77×	45×	27×	22×	42×	—

—, Not determined. 

^*Ratio of in vitro IC₅₀ values. 

^†Estimated ratio of IC₅₀ values. 

^‡Ratio of EC₅₀ values.