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Effect of AppCHClppA and ApspCHClppsA on TxB2 production in ADP- and arachidonic acid (AA)-stimulated platelets
| Agonist | TxB2, pg per 109 platelets
|
||||
|---|---|---|---|---|---|
| AppCHClppA
|
ApspCHClppsA
|
||||
| No inhibitor (saline control) | 5 μM | 10 μM | 2.5 μM | 5 μM | |
| ADP (5 μM) | 171 | 91 | 4 | 91 | 21 |
| AA (2 mM) | 376 | ND | 291 | ND | 219 |
ND, not done.
