Figure 5.

Electroencephalographic recordings. (A) Three animals (β3^−/−, β3^+/−, β3^+/+) were simultaneously recorded at 2 months of age. The β3^−/− record (Top) is abnormal, displaying abundant paroxysmal slow and sharp wave activity, in marked contrast to the normal pattern of β3^+/+ littermate controls (Bottom). β3^+/− mice display a pattern intermediate between that of β3^−/− and β3^+/+ records. (B) Seizure in β3^−/− mouse at 5 months of age, followed by suppression of electrocortical activity.