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. 1992 May;174(9):3092–3094. doi: 10.1128/jb.174.9.3092-3094.1992

The arsenical ATPase efflux pump mediates tellurite resistance.

R J Turner 1, Y Hou 1, J H Weiner 1, D E Taylor 1
PMCID: PMC205967  PMID: 1533216

Abstract

The ars operon of the resistance plasmid R773 was found to produce moderate levels of resistance to tellurite. A MIC of 64 micrograms of TeO3(2-) per ml was found for Escherichia coli cells harboring plasmids which contained all three of the structural genes (arsA, arsB, and arsC) of the anion-translocating ATPase. MICs specified by plasmids carrying only one or two structural elements or the cloning vector alone were 2 to 4 micrograms/ml. The rate of TeO3(2-) uptake was found to be on the order of 55% less for cultures containing the resistance plasmids.

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Selected References

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