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. Author manuscript; available in PMC: 2007 Nov 5.
Published in final edited form as: Brain Behav Immun. 2007 Feb 9;21(5):581–591. doi: 10.1016/j.bbi.2006.12.003

Figure 1. The effects of ddC on paw withdrawal thresholds in response to mechanical stimulation.

Figure 1

Baseline responses to tactile stimulation with von Frey filaments were determined before NRTI injection and for 3-42 days following NRTI treatment. Each bar represents the combined bilateral changes in mean threshold force (±SE) eliciting a withdrawal to mechanical indentation of the hindpaw. The threshold force was significantly reduced starting 3 days after the intraperitoneal injection of ddC, and lasted through 42 days (*, p<0.001, n=12).