Table 2. Patient outcomes and immune response to vaccines.
Subjects are stratified by clinical status at the time of the report. Upper table: no evidence of disease (NED; n=9). Lower table: recurrence / progression (n=5). Site of recurrent / progressive disease and status of the subject at the time of the repost is noted. Immunologic response measured by IFN-γ ELISPOT is indicated by positive ( + ; n=9) or negative ( − ; n=5). Stage grouping of TNM subsets is shown for each subject. Also shown is months from completion of definitive therapy and months from second vaccine at the time of the report.
Patient number |
Stage |
Months from conventional treatment |
Months from 2nd vaccine |
Recurrence from 2nd vaccine (months) |
Status at time of report |
Immunologic Response |
---|---|---|---|---|---|---|
DC17 | IB | 51 | 23 | - | NED | + |
DC18 | IIIB | 51 | 24 | - | NED | + |
DC20 | IA | 33 | 22 | - | NED | − |
DC22 | IIIA | 27 | 18 | - | NED | − |
DC24 | IIIA | 23 | 18 | - | NED | + |
DC26 | IA | 32 | 14 | - | NED | + |
DC27 | IA | 38 | 13 | - | NED | + |
DC28 | IB | 28 | 13 | - | NED | + |
DC29 | IIB | 17 | 12 | - | NED | + |
DC19 | IIIB | Expired 12 |
Expired 6 |
3 | Progression Loco-regional Expired |
− |
DC21 | IIIB/IV | Expired 6 |
Expired 2 |
2 | Progression Loco-regional Expired |
+ |
DC23 | IB | 25 | 17 | 3 | Metastasis Skeletal Stable |
+ |
DC25 | IIIA | Expired 7 |
Expired 2 |
<1 | Progression Loco-regional Expired |
− |
DC30 | IIIB | 21 | 10 | 1 | Metastasis Brain Stable |
− |