TABLE 1.
Clone | VL | %Identitya | JL | L3(aa)b | IGHV | %Identitya | Isotype | JH | H3b | Familyc |
---|---|---|---|---|---|---|---|---|---|---|
11A11 | IGKV1-5 | 96.5 | Jκ2 | 8 | IGHV1-18 | 95.8 | IgG1 | JH4 | 18 | H1-18 |
4A12 | IGKV1D-39 | 95.6 | Jκ4 | 9 | IGHV1-46 | 91.7 | IgG3 | JH4 | 12 | H1-46 |
34E3 | IGLV1-40 | 95.0 | Jλ3 | 12 | IGHV3-15 | 94.1 | IgG1 | JH1 | 13 | H3-15 |
35F7 | IGLV1-40 | 97.6 | Jλ3 | 12 | IGHV3-15 | 98.5 | IgG1 | JH1 | 13 | |
40D10 | IGLV1-40 | 94.7 | Jλ3 | 12 | IGHV3-15 | 96.3 | IgG1 | JH1 | 13 | |
41A3 | IGLV1-40 | 96.1 | Jλ3 | 12 | IGHV3-15 | 97.0 | IgG1 | JH1 | 13 | |
41C5 | IGLV1-40 | 96.5 | Jλ3 | 12 | IGHV3-15 | 93.7 | IgG1 | JH1 | 13 | |
46D1 | IGLV1-40 | 97.3 | Jλ3 | 12 | IGHV3-15 | 94.1 | IgG1 | JH1 | 13 | |
49F1 | IGLV1-40 | 96.8 | Jλ3 | 12 | IGHV3-15 | 94.1 | IgG1 | JH1 | 13 | |
51D6 | IGLV1-40 | 97.3 | Jλ3 | 12 | IGHV3-15 | 93.7 | IgG1 | JH1 | 13 | |
52E7 | IGLV1-40 | 97.5 | Jλ3 | 12 | IGHV3-15 | 91.5 | IgG1 | JH1 | 13 | |
53H4 | IGLV1-40 | 98.8 | Jλ3 | 12 | IGHV3-15 | 94.1 | IgG1 | JH1 | 13 | |
54C7 | IGLV1-40 | 99.1 | Jλ3 | 12 | IGHV3-15 | 94.8 | IgG1 | JH1 | 13 | |
55C7 | IGLV1-40 | 97.6 | Jλ3 | 12 | IGHV3-15 | 92.6 | IgA1 | JH1 | 13 | |
56F6 | IGLV1-40 | 95.0 | Jλ3 | 12 | IGHV3-15 | 94.1 | IgG1 | JH1 | 19 | |
59H10 | IGLV1-40 | 97.6 | Jλ3 | 12 | IGHV3-15 | 94.5 | IgG1 | JH1 | 13 | |
65A8 | IGLV1-40 | 98.8 | Jλ3 | 12 | IGHV3-15 | 94.1 | IgG1 | JH1 | 13 | |
65G8 | IGLV1-40 | 96.5 | Jλ3 | 12 | IGHV3-15 | 94.5 | IgG1 | JH1 | 13 | |
65H8 | IGLV1-40 | 97.6 | Jλ3 | 12 | IGHV3-15 | 94.8 | IgG1 | JH1 | 13 | |
66A5 | IGLV1-40 | 94.7 | Jλ3 | 12 | IGHV3-15 | 94.8 | IgG1 | JH1 | 13 | |
66B2 | IGLV1-40 | 95.9 | Jλ3 | 12 | IGHV3-15 | 93.7 | IgG1 | JH1 | 13 | |
17D2 | IGKV1-9 | 98.4 | Jκ4 | 9 | IGHV3-30 | 95.1 | IgG1 | JH3 | 15 | H3-30a |
65A3 | IGLV3-1 | 99.7 | Jλ3 | 9 | IGHV3-30 | 94.3 | IgG1 | JH6 | 17 | H3-30b |
47F12 | IGLV1-44 | 96.7 | Jλ3 | 11 | IGHV3-30 | 94.0 | IgG1 | JH6 | 18 | H3-30c |
59G5 | IGLV1-44 | 97.0 | Jλ3 | 11 | IGHV3-30 | 94.0 | IgG1 | JH6 | 18 | |
8H2 | IGKV6-21 | 96.3 | Jκ2 | 9 | IGHV3-33 | 94.7 | IgG1 | JH4 | 13 | H3-33a |
19E1 | IGKV6-21 | 99.1 | Jκ2 | 9 | IGHV3-33 | 94.7 | IgG1 | JH4 | 13 | |
41F12 | IGLV1-47 | 97.3 | Jλ1 | 11 | IGHV3-33 | 95.1 | IgG1 | JH4 | 12 | H3-33b |
55F9 | IGLV1-47 | 97.0 | Jλ1 | 11 | IGHV3-33 | 95.8 | IgG1 | JH4 | 12 | |
20C7 | IGKV1-9 | 99.4 | Jκ2 | 9 | IGHV3-43 | 95.8 | IgG1 | JH6 | 17 | H3-43 |
51C5 | IGLV3-21 | 97.6 | Jλ2 | 11 | IGHV3-74 | 95.8 | IgG1 | JH4 | 14 | H3-74 |
1A5 | IGKV2-30 | 97.6 | Jκ1 | 9 | IGHV4-59 | 90.8 | IgG1 | JH1 | 11 | H4-59 |
1B10 | IGKV2-30 | 97.3 | Jκ1 | 9 | IGHV4-59 | 90.8 | IgA1 | JH1 | 11 | |
4B1 | IGKV2-30 | 97.3 | Jκ1 | 9 | IGHV4-59 | 90.8 | IgG1 | JH1 | 11 | |
13E12 | IGKV2-30 | 97.3 | Jκ1 | 9 | IGHV4-59 | 90.8 | IgG2 | JH1 | 11 |
Percent nucleotide identity over the entire V region as compared to the corresponding germline gene.
Number of residues comprising the VL and IGHV CDR3 region; aa = amino acids.
Family denotes unique IGHV rearrangements