Table 2.
Genes most differentially expressed in SCL-LMO1 T-cell tumors
| Fold increase | Gene | Description |
|---|---|---|
| 15.6 | Ftl1 | ferritin light chain 1 (Ftl1), mRNA. |
| 15.0 | Cfl1 | cofilin 1, non-muscle (Cfl1), mRNA. |
| 11.5 | Tcrb | T cell receptor beta chain mRNA, partial cds. |
| 11.0 | Hspa8 | heat shock protein 8 (Hspa8), mRNA. |
| 11.0 | Lmo1 | LIM domain only 1 (Lmo1), mRNA. |
| 10.9 | Eef1a1 | Eukaryotic translation elongation factor 1 alpha 1 |
| 10.7 | Tuba7 | tubulin, alpha 7 (Tuba7), mRNA. |
| 10.4 | Eef-tu | Mouse eEF-Tu gene encoding elongation factor Tu |
| 9.4 | Ef2 | Elongation factor 2 (EF-2) (LOC673429), mRNA. |
| 9.2 | Igh-6 | Immunoglobulin heavy chain 6 (heavy chain of IgM) |
| 8.9 | Gapdh | glyceraldehyde-3-phosphate dehydrogenase |
| 8.4 | Dtx1 | deltex 1 homolog (Drosophila) (Dtx1), mRNA. |
| 8.4 | Cnbp2 | cellular nucleic acid binding protein 2 (Cnbp2), mRNA. |
| 8.2 | Tubb5 | tubulin, beta 5 (Tubb5), mRNA. |
| 8.0 | Zmym1 | zinc finger, MYM domain containing 1 (Zmym1), mRNA. |
| 7.9 | Siglece | sialic acid binding Ig-like lectin E (Siglece), mRNA. |
| 7.8 | Eif4a1 | eukaryotic translation initiation factor 4A1 (Eif4a1), mRNA. |
| 7.6 | Bzw2 | basic leucine zipper and W2 domains 2 (Bzw2), mRNA. |
| 7.5 | Eef2 | eukaryotic translation elongation factor 2 (Eef2), mRNA. |
| 7.2 | Eif5a | eukaryotic translation initiation factor 5A (Eif5a), mRNA. |
| 6.8 | Tcf7 | transcription factor 7, T-cell specific (Tcf7), mRNA. |
| 6.3 | Aes | amino-terminal enhancer of split (Aes), mRNA. |
| 6.3 | Iltifb | interleukin 10-related T cell-derived inducible factor beta (Iltifb) |
| 6.3 | Tcra | T-cell receptor alpha chain (TCRA) |
| 6.0 | Coro1a | coronin, actin binding protein 1A (Coro1a), mRNA. |
| 5.5 | Pin1 | protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 (Pin1), mRNA. |
| 5.4 | Cdk4 | cyclin-dependent kinase 4 (Cdk4), mRNA. |
| 5.4 | Tceal8 | Transcription elongation factor A (SII)-like 8 |
| 5.3 | Map2k4 | mitogen activated protein kinase kinase 4 (Map2k4), mRNA. |
| 5.1 | Eif4b | eukaryotic translation initiation factor 4B (Eif4b), mRNA. |
| 5.0 | Ccl8 | chemokine (C-C motif) ligand 8 (Ccl8), mRNA. |
| 4.8 | Dap | death-associated protein (Dap), mRNA. |
| 4.7 | Dennd2d | DENN/MADD domain containing 2D (Dennd2d), mRNA. |
| 4.5 | Mrpl38 | mitochondrial ribosomal protein L38 (Mrpl38), mRNA. |
| 4.3 | Rpl13 | Ribosomal protein L13 |
| 4.3 | Hnrpu | heterogeneous nuclear ribonucleoprotein U (Hnrpu), mRNA. |
| 4.3 | Notch1 | Notch gene homolog 1 (Drosophila) |
| 4.2 | Hnrpl | heterogeneous nuclear ribonucleoprotein L (Hnrpl), mRNA. |
| Fold decrease | Gene | Description |
| 6.1 | Cd83 | CD83 antigen (Cd83), mRNA. |
| 6.1 | Prr6 | Proline-rich polypeptide 6 |
| 6.4 | Erf1 | Mus musculus ETS-related transcription factor ERF (Erf1) mRNA |
| 6.5 | Krt2-8 | keratin complex 2, basic, gene 8 (Krt2-8), mRNA. |
| 6.6 | Mgst1 | microsomal glutathione S-transferase 1 (Mgst1), mRNA. |
| 6.6 | Ucp1 | uncoupling protein 1 (mitochondrial, proton carrier) (Ucp1), mRNA. |
| 6.8 | Fabp3 | fatty acid binding protein 3, muscle and heart (Fabp3), mRNA. |
| 6.9 | Diras2 | DIRAS family, GTP-binding RAS-like 2 (Diras2), mRNA. |
| 7.0 | Cox7a1 | cytochrome c oxidase, subunit VIIa 1 (Cox7a1), mRNA. |
| 8.5 | Slc18a3 | solute carrier family 18 (vesicular monoamine), |
| 10.7 | Fabp4 | Fatty acid binding protein 4, adipocyte |
| 11.3 | Cdo1 | cysteine dioxygenase 1, cytosolic (Cdo1), mRNA. |
| 11.3 | Cox8b | cytochrome c oxidase, subunit VIIIb (Cox8b), mRNA. |
| 11.6 | Fabp9 | Fatty acid binding protein 9, testis |
| 12.1 | Prss16 | protease, serine, 16 (thymus) (Prss16), mRNA. |
| 12.3 | Cidea | cell death-inducing DNA fragmentation factor, alpha subunit |
| 14.3 | Dgat2 | diacylglycerol O-acyltransferase 2 (Dgat2), mRNA. |
| 15.7 | Ccl25 | Chemokine (C-C motif) ligand 25 |
| 20.3 | Snap25 | Synaptosomal-associated protein 25 |
*
some genes between 4 and 6-fold upregulated not listed due to space limitations