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In vitro interaction of native dynactin complex with MTs and the effect of tau. (A) SDS–PAGE of proteins in the pellet (P) and supernatant (S), when purified native pig brain dynactin was incubated with MT assembled from purified pig brain tubulin, with or without recombinant tau1–13. (B) Integrated densities (in arbitrary units) obtained by densitometry of p150 bands in the pellet lanes of panel A.
