Table 2.
Polycation | N:P | Mw (×10-8) (g/mol) | RG (nm) | RH (nm) | ζ (mV) | d (g/mL)* | n** |
---|---|---|---|---|---|---|---|
rPDMAEMA1 | 0.75 | 10.8 | 122 | -- | -30 | 0.236 | 179 |
1.2 | 7.40 | 113 | 109 | 46 | 0.203 | 113 | |
2 | 2.89 | 98 | 80 | 51 | 0.123 | 44 | |
4 | 1.44 | 83 | 70 | 42 | 0.101 | 22 | |
rPDMAEMA2 | 0.75 | 5.21 | 114 | 109 | -35 | 0.138 | 87 |
1.2 | 5.96 | 114 | 116 | 39 | 0.158 | 91 | |
2 | 2.35 | 99 | 78 | 48 | 0.095 | 36 | |
4 | 1.37 | 87 | 66 | 50 | 0.084 | 21 | |
PDMAEMA1 | 0.75 | 8.69 | 121 | 132 | -28 | 0.196 | 144 |
1.2 | 11.7 | 120 | -- | 35 | 0.268 | 179 | |
2 | 3.75 | 100 | 81 | 49 | 0.149 | 57 | |
4 | 1.83 | 84 | 66 | 53 | 0.123 | 28 | |
PDMAEMA2 | 0.75 | 10.5 | 124 | -- | -27 | 0.218 | 175 |
1.2 | 7.42 | 112 | 102 | 47 | 0.212 | 113 | |
2 | 3.61 | 97 | 79 | 54 | 0.159 | 55 | |
4 | 2.01 | 84 | 69 | 44 | 0.137 | 31 |
Calculated from d = 3Mw/(4πNARG3)
Estimated average number of DNA molecules per one polyplex