Table I. Rates of cell survival as a function of DSB localization in nup mutants.
WT | Δnup145C | Δnup84 | Δnup120 | ΔDnup133 | ΔDnup170 | |
---|---|---|---|---|---|---|
Subtelomere XI-L | 3.7 ± 0.4 | 0.3 ± 0.1 | 1.1 ± 0.4 | 2.2 ± 0.3 | 2.2 ± 0.1 | 2.9 ± 0.2 |
Central XI | 0.16 ± 0.06 | 0.19 ± 0.09 | 0.12 ± 0.06 | nd | nd | 0.17 ± 0.03 |
Central XV | 1.3 ± 0.09 | 1.15 ± 0.06 | nd | nd | nd | nd |
Central XV (GC) | 73.6 ± 4.2 | 77 ± 5.2 | nd | nd | nd | nd |
Cell survival is expressed as the ratio between the number of colonies formed after induction of I-SceI in galactose versus the number of colonies present on glucose. Standard errors with a P value of 0.1 are shown. Position of the DSB along a chromosome and number of the chromosome are indicated in the first column, GC stands for gene conversion; strain genetic backgrounds are given on the top; nd, not determined.