Table 2.
Conservation of stem cell aging in the local organ niche
Rate of proliferation ESC/ASC (percentage of BrdU) | Myogenic differentiation ESC/ASC (percentage of desmin) | |
---|---|---|
Young myofiber | 60.2 ± 2.5, 40.5 ± 2.6 | 7.4 ± 0.9, 47.6 ± 5.0 |
Old myofiber | 30.1 ± 4.3, 21.5 ± 4.1 | 1.3 ± 0.7, 19.7 ± 4.7 |
Quantified results from Fig. 4 are summarized and presented as mean percentages from experimental replicates ± SE. Rate of proliferation (BrdU) and myogenic differentiation (desmin) are shown for both ESCs and ASCs, in the presence of young vs. old differentiated muscle environments (young myofiber or old myofiber).