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. 2006 Feb 27;172(5):771–782. doi: 10.1083/jcb.200512115

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Copyright © 2006, The Rockefeller University Press

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Figure 3. — Monolayer wound assays demonstrate enhanced migration of fibroblasts lacking zyxin. A wound was scraped across monolayer wild-type and zyxin-null fibroblasts, and migration was monitored by time-lapse microscopy. (A) Time points (0, 4, 8, and 12 h) of wild-type fibroblasts (top) and zyxin−/− fibroblasts (bottom). (B) The results were examined in a blind fashion and converted into rate measurements (the distance to the midline of the wound over the time it took for cells to reach the midline; mean ± SEM; n = 4). Primary MEFs were used for wound assays. **, P < 0.005.