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. 2006 May 8;173(3):373–381. doi: 10.1083/jcb.200510097

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Copyright © 2006, The Rockefeller University Press

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Figure 7. — Axonal growth by LVT and intercalated addition. (A) Docked mitochondria and cytoskeletal elements are embedded in the axonal framework. (B) Tension generated by forces at the growth cone leads to viscoelastic stretching/creep and an initial decrease in the density of cytosolic components. LVT, as indicated by the gray arrows, is occurring with a flux profile that increases along the axon. (C) Intercalated addition by fast transport restores cytosolic density. Fast flux, as indicated by the arrows, deposits mitochondria in an intercalated fashion and decreases along the axon.