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Effect of PAK activation on WT-paxillin dynamics in CHO-K1 cells
| Expressed protein | Apparent t
1/2
(adhesion formation) |
t
1/2
(adhesion disassembly) |
|---|---|---|
| min | min | |
| WT-pax | 9.5 ± 0.5 | 6 ± 2.5 |
| KD-PAK + WT-pax | 18.0 ± 1.5 | 18.8 ± 1.6 |
| CA-PAK + WT-pax | <1 | <1 |
t 1/2 is reported as means ± SEM. For each t 1/2 determination, measurements were obtained for 15–20 individual adhesions on four to six cells from three independent experiments.
