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Effect of Rac activation on S273D- and WT-paxillin dynamics
| Expressed protein | t 1/2 (adhesion disassembly) |
|---|---|
| min | |
| S273D-pax | <1 |
| N17Rac + S273D-pax | 15.9 ± 0.8 |
| V12Rac + WT-pax | nd |
| Tiam1 + S273D-pax | <1 |
t 1/2 is reported as means ± SEM. For each t 1/2 determination, measurements were obtained for 15–20 individual adhesions on four to six cells from three independent experiments. nd represents stable adhesions that did not turn over at all.
