Figure 9.

Scheme depicting the development and dynamics of peroxisome–lipid body interactions. (left and bottom) Peroxisomes bind to lipid bodies (LBs) and stimulate the breakdown of triglycerides, releasing fatty acids (green lines) that get imported and oxidized by peroxisomes. Peroxisome invasion into the lipid body is also shown. (top) Peroxisomes that are unable to perform β oxidation cause the accumulation of fatty acids, resulting in gnarls. (box) Peroxisome invasion into lipid bodies. (A) A peroxisome (P) with its phospholipid bilayer approaches the lipid body monolayer. (B) A hemifusion event occurs, resulting in invasion of the lipid core by the peroxisomal membrane inner leaflet (C). Small arrows indicate the flux of fatty acids into peroxisomes for oxidation.