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. 2006 Jun 19;173(6):853–859. doi: 10.1083/jcb.200602046

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Copyright © 2006, The Rockefeller University Press

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Figure 2. — Down-regulation of PDI-like proteins. (A) Structural organization of PDI, ERp72, and ERp57. (B) PDI, ERp72, ERp57, and ERp29 protein levels were examined in wild-type (WT), PDI⁻, ERp72⁻, and ERp57⁻ cells. (C) Wild-type, PDI⁻, ERp72⁻, and ERp57⁻ cells were incubated with 2 μg/ml tunicamycin (TM) for 8 h, and BiP expression was assessed by SDS-PAGE and immunoblot analysis. BiP is 78 kD.