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. 2007 Jan 29;176(3):263–268. doi: 10.1083/jcb.200611056

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Copyright © 2007, The Rockefeller University Press

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Figure 1. — Differential trafficking of wild-type and ΔinvA/Inv S. Typhimurium. (A) Cells were infected with wild type (♦), ΔinvA/Inv (▪), or ΔinvA/Inv + tetracycline (•). Semi-log plot of the relative number of intracellular bacteria over an 8-h infection. Results are the means (± SD) of three independent experiments. HeLa cells were transfected with CFP-Rab8B (B) or CFP-Rab5B (C), infected with wild-type or ΔinvA/Inv S. Typhimurium, and fixed at the indicated time. Arrows indicate colocalization between bacterial vacuole and Rab. Arrowheads indicate extracellular bacteria. Bar, 10 μm.