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. 2007 Apr 9;177(1):87–101. doi: 10.1083/jcb.200611114

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Copyright © 2007, The Rockefeller University Press

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Figure 2. — A latent or actively dividing proliferative compartment is delineated by laminin-2/4 in lobules. Immunoperoxidase staining of ducts (left) and lobules (right) in cryostat sections of the human breast with Ki-67 (a and b) and laminin-2/4 (c and d). Staining with Ki-67 can approach 50% of the nuclei in lobules as opposed to a mean of 2.8% in ducts. Staining with laminin-2/4 is confined to lobules (brown). Nuclei are counterstained with hematoxylin (blue). Bars, 50 μm.