Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2006 Sep 11;174(6):803–813. doi: 10.1083/jcb.200604014

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2006, The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 6. — Ultrastructural localization of HRP-STIM1 in control and store-depleted Jurkat cells. (A–C) In resting cells with full Ca²⁺ stores, HRP-STIM1 was localized in tubules throughout the cytoplasm, having a similar distribution as tubules marked by HRP-ER (Fig. 5, A and B). (D–H) In cells treated with 1 μM TG for 15 min to deplete stores, HRP-STIM1 was concentrated in tubules closely associated with the plasma membrane (arrows), whereas weak, diffuse staining was observed in cytoplasmic ER tubules (arrowheads). m, mitochondrion; n, nucleus; pm, plasma membrane. Bars: (A, D, and E) 2 μm; (A [inset], B, C, F, and G) 200 nm; (H) 100 nm.