Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2006 Sep 11;174(6):815–825. doi: 10.1083/jcb.200604015

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2006, The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 2. — Fluo-5F fluorescence signals arise from CRAC channels. Pseudocolor images indicate ΔF/F₀ at –122 mV from three cells as described in Fig. 1 A. ΔF/F₀ signals (left) and membrane currents (middle) are inhibited by 2-APB (A) and La³⁺ (B). (C) ΔF/F₀ signals are absent in CRAC-deficient CJ-1 Jurkat cells. The slight suppression of fluorescence by 10 μM La³⁺ is consistent with the residual amount of I_CRAC observed in CJ-1 cells. The graphs on the right show that the ΔF/F₀ signals vary in proportion to I_CRAC for all conditions. A, n = 6 cells; B, n = 4 cells; C, n = 4 cells.