Table III.
Velocity of IFT particle proteins in bbs and kinesin-2 mutant animals
| Anterograde motility | Mean velocities
|
||||
|---|---|---|---|---|---|
| Strain | Initial segment | n | Distal segment | n | |
| μm/s −1 | μm/s −1 | ||||
| IFT-A | |||||
| CHE-11∷GFP | Wild typea | ∼0.70 | ∼1.30 | ||
| bbs-7 or bbs-8 a | ∼0.50–0.60 | None | |||
| bbs-7;osm-3 | 0.56 ± 0.06 | 103 | None | ||
| bbs-8;osm-3 | 0.52 ± 0.05 | 110 | None | ||
| bbs-7;klp-11 | 1.27 ± 0.16 | 103 | 1.34 ± 0.17 | 107 | |
| bbs-8;klp-11 | 1.26 ± 0.19 | 101 | 1.34 ± 0.19 | 104 | |
| IFT-B | |||||
| CHE-2∷GFP | Wild typea | ∼0.70 | ∼1.30 | ||
| bbs-7 or bbs-8 a | ∼1.10–1.30 | ∼1.30 | |||
| bbs-7;klp-11 | 1.30 ± 0.18 | 107 | 1.35 ± 0.18 | 102 | |
| bbs-8;klp-11 | 1.22 ± 0.17 | 110 | 1.28 ± 0.16 | 104 | |
| bbs-7;osm-3 | 0.51 ± 0.07 | 105 | None | ||
| bbs-8;osm-3 | 0.55 ± 0.06 | 102 | None | ||
| OSM-6∷GFP | Wild typeb | ∼0.70 | ∼1.30 | ||
| osm-3 b | ∼0.50 | None | |||
| klp-11 | 1.28 ± 0.15 | 107 | 1.33 ± 0.15 | 106 | |
| bbs-7 | 1.18 ± 0.17 | 104 | 1.32 ± 0.19 | 101 | |
| bbs-7;osm-3 | 0.55 ± 0.07 | 109 | None | ||
| bbs-7;klp-11 | 1.28 ± 0.16 | 100 | 1.22 ± 0.17 | 101 | |