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. 2007 Jul 16;178(2):309–322. doi: 10.1083/jcb.200701030

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Copyright © 2007, The Rockefeller University Press

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Figure 10. — Eps15 is a functional binding partner of Dap160. (A) With single stimuli at 5 mM Ca²⁺, dap160 ^Δ1 eps15^e75/Df(2L)bur-K1 eps15^Δ29 double mutants (dap160 and eps15 null) show normal EJP. (B) When stimulated at 10 Hz in 5 mM Ca²⁺, dap160- and eps15-null double mutants show synaptic depression kinetics that overlap with eps15^e75/eps15^Δ29 (eps15 null) and dap160 ^Δ1/Df(2L)bur-K1(dap160 null) single mutants. (shibire^ts1 34°C recordings are taken from Koh et al. [2004] for comparison.) (C) dap160- and eps15-null double mutants show reductions in FM1-43FX uptake similar to eps15- and dap160-null single mutants. w adults or larvae were used as controls. Error bars indicate SEM, and the numbers in histograms indicate the number of larvae.