Figure 2.
Loss of APQ12 causes the severe mislocalization of cytoplasmic filament Nups. Localizations of various Nups at 23°C in a WT versus apq12Δ background. Images for Nup159/Rat7 and Pom152 were from indirect IF experiments using antibodies directed against the respective proteins; all others were viewed via live microscopy using Nup-GFP fusions. DIC, differential interference contrast.