Table I.
Synthetic interactions of apq12Δ
| Relevant genotype | 23°C | 30°C | 34°C | 37°C |
|---|---|---|---|---|
| apq12Δ | ++ | +++ | +++ | +++ |
| rat8-2 (dbp5) apq12Δ/rat8-2 | ++ + | +++ + | + − | − − |
| mex67-5 apq12Δ/mex67-5 | ++ ++ | +++ +++ | + + | − − |
| rat7ΔN(nup159ΔN apq12Δ/rat7ΔN | ++ + | +++ + | ++ + | − − |
| gle1-37(rss1-37) apq12Δ/gle1-37 | ++ + | ++ ++ | − − | − − |
| nup42Δ (rip1Δ) apq12Δ/nup42Δ | +++ +++ | +++ +++ | +++ +++ | +++ +++ |
| nup116Δ apq12Δ/nup116Δ | ++ + | ++ + | + + | − − |
| nup120Δ apq12Δ/nup120Δ | ++ + | +++ + | + − | − − |
| nup85Δ apq12Δ/nup85Δ | ++ + | +++ + | + − | − − |
| nup188Δ apq12Δ/nup188Δ | +++ + | +++ + | +++ + | +++ − |
| nup170Δ apq12Δ/nup170Δ | ++ + | +++ + | +++ + | +++ − |
| nup100Δ apq12Δ/nup100Δ | +++ ++ | +++ +++ | +++ +++ | +++ +++ |
| nup59Δ apq12Δ/nup59Δ | +++ +++ | +++ +++ | +++ +++ | +++ +++ |
| nup2Δ apq12Δ/nup2Δ | +++ ++ | +++ ++ | +++ ++ | +++ ++ |
| nup60Δ apq12Δ/nup60Δ | +++ ++ | +++ ++ | +++ ++ | +++ ++ |
| pom34Δ apq12Δ/pom34Δ | +++ + | +++ ++ | +++ ++ | +++ ++ |
| pom152Δ apq12Δ/pom152Δ | +++ + | +++ ++ | +++ + | +++ + |
| ndc1-39 apq12Δ/ndc1-39 | +++ + | ++ + | + − | − − |
Synthetic interaction chart for strains that contain the apq12Δ disruption in combination with mutations in genes coding for Nups and Nup-associated proteins. +++, WT growth; ++ and +, synthetically sick; −, synthetically lethal.