Figure 1.
SEL1L is part of a conserved complex in many cell types. Immunoprecipitation from digitonin lysates of HeLa (lanes 1–4) or MM1.S (lanes 5–8) cells pulse-labeled for 16 h (steady state) were performed with control rabbit IgG, anti–Derlin-1, anti–Derlin-2, and anti-SEL1L antibodies, respectively. The positions of the relevant proteins are indicated.